resistant strain — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2027	Oxysanguinarine	8-Oxosanguinarine,Hydroxysanguinarine	Parasite
	Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.		Parasite
T7700	Lersivirine	Lersivirine(UK 453061),UK-453061	HIV Protease , Reverse Transcriptase
	Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.		HIV Protease , Reverse Transcriptase
T15409	GNF179		Parasite
	GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.		Parasite
T11888	LtaS-IN-1		Others , Antibacterial
	LtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 is against Enterococcus spp 28 strains with varying MIC value...		Others , Antibacterial
T37341	N-Acetyltyramine		Antibacterial
	N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml...		Antibacterial
T11445	GNF179 (Metabolite)	GNF179 Metabolite	Others
	GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral ...		Others
T3831	Licoricone		Antifection
	Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.		Antifection
TN3583	Canophyllal		Antifection
	Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs.		Antifection
T72717	Anti-IAV agent 1
	Anti-IAV Agent 1-1a is an orally administered compound effective against the Influenza A virus (IAV), demonstrating inhibitory concentration 50 (IC50) values of 0.03 μM and 0.06 μM for the H1N1 strain and the Oseltamivir...
T80395	Abaecin
	Abaecin, an antibacterial peptide, exhibits selective efficacy against an Apidaecin-resistant strain of Xanthomonas [1].
TN3907	Pinosylvin monomethyl ether	(E)-3-Hydroxy-5-methoxystilbene	Antifection
	(E)-3-Hydroxy-5-methoxystilbene possesses inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium bovis BCG, and avirulent Bacil...		Antifection
T62600	RYL-552S
	RYL-552S is a drug-resistant strain of Plasmodium falciparum that effectively kills the asexual blood stage of the parasite in vitro.
TMA2418	1-Methoxyphaseollidin		PAFR , Antifection
	1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity agains...		PAFR , Antifection
TN2311	Wulignan A1		Antifection
	Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities.		Antifection
T63865	Antimycobacterial agent-3
	Antimycobacterial agent-3 is an antimycobacterial agent with low cytotoxicity. antimycobacterial agent-3 is effective against sensitive MTB strain H37Rv and resistant clinical isolates (MIC < 0.029-0.110 μ M).
T81318	R-30-Hydroxygambogic acid
	R-30-Hydroxygambogic acid, a polyprenylated xanthone epimer isolated from the gamboge of Garcinia hanburyi, exhibits cytotoxicity against human leukemia K562 cell lines, with IC50 values of 2.89 μM for the resistant stra...
T35485	6-Prenylindole
	6-Prenylindole is a bacterial metabolite that has been found in Streptomyces and has antifungal and antimalarial properties.1 It is active against A. brassicicola strain TP-F0423 and F. oxysporum f. sp. tulipae TU-4-2 (1...
T60302	4,4'-Dicyanostilbene
	4,4'-Dicyanostilbene (compound 43) demonstrates potent antimalarial activity against the Dd2 strain, exhibiting an EC50 value of 27 nM, and exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (M...
TN4113	Garcinone E		Antifection
	Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent...		Antifection
T79379	Antitubercular agent-39
	Antitubercular agent-39 (Compound P1) is a potent agent effective against both drug-resistant strains and drug-susceptible clinical isolates of tuberculosis, exhibiting inhibition of the Mtb strain H37Rv with a minimum i...